Dual specificity protein phosphatase CDC14A, CDC14 cell division cycle 14 homolog A, CDC14A
Product description
The protein encoded by this gene is a member of the dual
specificity protein tyrosine phosphatase family. It is highly
similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine
phosphatase involved in the exit of cell mitosis and initiation of
DNA replication, suggesting a role in cell cycle control. This
protein has been shown to interact with, and dephosphorylate tumor
suppressor protein p53, and is thought to regulate the function of
p53. Alternative splicing of this gene results in several
transcript variants encoding distinct isoforms. [provided by
RefSeq].1) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Immunogen
This CDC14A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-500 amino acids from the C-terminal region of human CDC14A.
Western blot analysis in A549 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.