Application
Western blot analysis in mouse stomach tissue lysates (35ug/lane).Application
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).| Product Name | CDC42EP2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Cdc42 effector protein 2, Binder of Rho GTPases 1, CDC42EP2, BORG1, CEP2 |
| Product description | CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control.1) Xue, Y., et al. Int. J. Cancer 118(12):2965-2972(2006) |
| Immunogen | This CDC42EP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-160 amino acids from the C-terminal region of human CDC42EP2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CDC42EP2 |
|---|---|
| Alternative Names | Cdc42 effector protein 2 Binder of Rho GTPases 1 CDC42EP2 BORG1 CEP2 |
| Molecular Weight(MW) | 22 kDa |
Application
Western blot analysis in mouse stomach tissue lysates (35ug/lane).
Application
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
