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CDH3 Antibody

Catalog Number:OM275115
OM275115
Discount Price
OM275115-100ul
1~2 Week
100ul
OM275115-50ul
50ul
OM275115-20ul
20ul
1~2 Week
Product Profile
Product Name CDH3 Antibody
Antibody Type Primary Antibodies
Antigen Alias Cadherin-3, Placental cadherin, P-cadherin, CDH3, CDHP
Product description CDH3 is a classical cadherin from the cadherin superfamily. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in the gene encoding CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.1) Indelman,M., Clin. Exp. Dermatol. 32 (2), 191-196 (2007)
Immunogen This CDH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 660-688 amino acids from the C-terminal region of human CDH3.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications IHC-PWB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50:
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CDH3
Alternative Names Cadherin-3
Placental cadherin
P-cadherin
CDH3
CDHP
Molecular Weight(MW) 91 kDa
Database Links
Entrez Gene 1001
Protein Accession P22223
Application

Application

Formalin-fixed and paraffin-embedded human prostate carcinoma tissue reacted with CDH3 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Application

Western Blot at 1:1000 dilution + A431 whole cell lysate Lysates/proteins at 20 ug per lane.
Application Notes For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50:
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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