Application
Immunohistochemistry staining of CDK2 in placenta tissue using CDK2 Monoclonal Antibody.| Product Name | CDK2 Antibody, Monoclonal |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CDK2, CDC2, Cell devision kinase 2, Cell division protein kinase 2, CDC2-related protein kinase, Cell division kinase 2, p33 protein kinase, p33(CDK2), CDKN2, Cyclin-dependent kinase 2 |
| Product description | Cyclin-dependent kinase 2 (CDK2), a CDC2/CDK-type protein kinase, regulates cell-cycle transition from G1 to S phase. CDK2 activation requires formation of a heterodimer with cyclin A, D, or E and phosphorylation by CAK. CDK2 inhibition results from association with p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Two alternatively spliced variants and multiple transcription initiation sites have been reported. Inhibition of CDK2 has been suggested to help prevent chemotherapy-induced alopecia in cancer patients. |
| Immunogen | CDK2 monoclonal antibody was raised against recombinant CDK2 (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Mouse |
| Tested Applications | ELISAIHCIPWB |
| CDK2 antibody can be used in immunohistochemistry starting at 10 μg/mL.: |
|
| Species Reactivity | HumanMouseXenopus |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | CDK2 |
|---|---|
| Alternative Names | CDK2 CDC2 Cell devision kinase 2 Cell division protein kinase 2 CDC2-related protein kinase Cell division kinase 2 p33 protein kinase p33(CDK2) CDKN2 Cyclin-dependent kinase 2 |
| Tissue Specificity | Recognizes cdk2, Mr 33kD. Does not cross-react with other cdks. |
Application
Immunohistochemistry staining of CDK2 in placenta tissue using CDK2 Monoclonal Antibody.| Application Notes | CDK2 antibody can be used in immunohistochemistry starting at 10 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store CDK2 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | 0.1M Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05% sodium azide, before the addition of glycerol to 30% |
