Application
Immunohistochemistry staining of CDK4 in breast formlin-fixed paraffin-embedded) tissue using CDK4 Antibody.| Product Name | CDK4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CDK4, Cell division protein kinase 4, Crk3, Cyclin-dependent kinase 4, CMM3, p34/cdk4, PSK-J3 |
| Product description | CDK4, a CDC2/CDK-type protein kinase, regulates cell cycle G1 phase progression. CDK4 associates with and is regulated by D-type cyclins and the CDK inhibitor p16 (CDKN2A). Two alternatively spliced variants have been reported. CDK4 has been shown to phosphorylate the retinoblastoma protein, and mutations in the CDK4 gene have been linked to tumorigenesis in several types of cancers, including cutaneous malignant melanoma. |
| Immunogen | CDK4 antibody was raised against a peptide mapping to the carboxy terminus of CDK4 (Mouse). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCIPWB |
| CDK4 antibody can be used in ELISA starting at 1: 10000, Western Blot starting at 1: 500 - 1: 2000, immunohistochemistry starting at 1:200, and immunofluorescence starting at 1:200 - 1:1000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CDK4 |
|---|---|
| Alternative Names | CDK4 Cell division protein kinase 4 Crk3 Cyclin-dependent kinase 4 CMM3 p34/cdk4 PSK-J3 |
Application
Immunohistochemistry staining of CDK4 in breast formlin-fixed paraffin-embedded) tissue using CDK4 Antibody.| Application Notes | CDK4 antibody can be used in ELISA starting at 1: 10000, Western Blot starting at 1: 500 - 1: 2000, immunohistochemistry starting at 1:200, and immunofluorescence starting at 1:200 - 1:1000.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store CDK4 antibody undiluted at 4 ˚C. Do not freeze. |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 0.2% gelatin. |
