Application
Antibody used in IHC on Human Intestine.Application
Antibody used in WB on Human Jurkat 0.6 ug/ml.Application
Antibody used in IHC on Human kidney.| Product Name | CDK7 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CDK7, CAK1, HCAK, MO15, STK1, CDKN7, p39MO15 |
| Product description | Cdk7 is the catalytic subunit of the CDK-activating kinase (CAK) complex, a serine-threonine kinase. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive carboxyl-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Cdk7 is involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.1) Tassan, J.P., et al., (1994) J. Cell Biol. 127:467-478.. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDK7. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| CDK7 antibody can be used for detection of CDK7 by ELISA at 1:75000. CDK7 antibody can be used for detection of CDK7 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CDK7 |
|---|---|
| Alternative Names | CDK7 CAK1 HCAK MO15 STK1 CDKN7 p39MO15 |
| Molecular Weight(MW) | 39 kDa |
Application
Antibody used in IHC on Human Intestine.
Application
Antibody used in WB on Human Jurkat 0.6 ug/ml.
Application
Antibody used in IHC on Human kidney.| Positive Control | 1) Cat. No. 1205 - Jurkat Cell Lysate |
|---|---|
| Application Notes | CDK7 antibody can be used for detection of CDK7 by ELISA at 1:75000. CDK7 antibody can be used for detection of CDK7 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store CDK7 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
