Application
Immunohistochemistry staining of CDK7 in kidney tissue using CDK7 Antibody.| Product Name | CDK7 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CDK7, 39 kDa protein kinase, CDK-activating kinase, CDK-activating kinase 1, CDKN7, Cell division protein kinase 7, Cyclin-dependent kinase 7, HCAK, Protein kinase, Mpk-7, Serine/threonine kinase stk1, CAK, CAK1, Crk4, Kinase subunit of CAK, MO15, p39 Mo15 |
| Product description | CDK7, a CDC2/CDK type protein kinase, is the catalytic component of the Cdk-activating kinase (CAK) which acts as a regulator of cell cycle progression. CDK7 complexes with cyclin H and MAT1 to form CAK, and this multi-subunit protein phosphorylates the cyclin-dependent protein kinases CDC2/CDK1, CDK2, CDK4 and CDK6. CAK also associates with the transcription factor IIH (TFIIH) which functions in transcription initiation and DNA repair. TFIIH has been shown to be regulated by CDK8/cyclin C. |
| Immunogen | CDK7 antibody was raised against a modified peptide of CDK7 (Human). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IFIHC |
| CDK7 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:2000, and immunohistochemistry starting at 5 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CDK7 |
|---|---|
| Alternative Names | CDK7 39 kDa protein kinase CDK-activating kinase CDK-activating kinase 1 CDKN7 Cell division protein kinase 7 Cyclin-dependent kinase 7 HCAK Protein kinase Mpk-7 Serine/threonine kinase stk1 CAK CAK1 Crk4 Kinase subunit of CAK MO15 p39 Mo15 |
| Tissue Specificity | pSer167 pThr170 |
Application
Immunohistochemistry staining of CDK7 in kidney tissue using CDK7 Antibody.| Application Notes | CDK7 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:2000, and immunohistochemistry starting at 5 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store CDK7 antibody at -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 50% glycerol. |
