Application
Western blot analysis of CDO1 in rat liver tissue lysate with CDO1 antibody at (A) 1 and (B) 2 μg/ml.| Product Name | CDO1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | CDO1 (cysteine dioxygenase, type I) belongs to the cysteine dioxygenase family and is involved in organosulfur biosynthesis (1). CDO1 functions as a dioxygenase that uses iron and zinc as cofactors to catalyze the conversion of L-cysteine and oxygen to 3-sulfinoalanine (1,2). CDO1 exists as a monomer and is expressed at high levels in liver and placenta and at lower levels in brain, pancreas and heart (1). CDO1 is involved in pyruvate-, sulfate- and taurine-related metabolic pathways and is a crucial regulator of cysteine concentrations within the cell (3,4).1) McCann KP, Akbari MT, Williams AC, et al. Human cysteine dioxygenase type I: primary structure derived from base sequencing of cDNA. Biochim. Biophys. Acta 1994; 1209:107-10. |
| Immunogen | CDO1 antibody was raised against a 19 amino acid peptide near the amino terminus of human CDO1. The immunogen is located within amino acids 30 - 80 of CDO1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| CDO1 antibody can be used for detection of CDO1 by Western blot at 1 - 2 μg/ml. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CDO1 |
|---|---|
| Alternative Names | Cysteine dioxygenase type I CDO CDO-I Cysteine dioxygenase type 1 |
| Molecular Weight(MW) | Predicted: 22 kDa Observed: 24 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Bovine: (84%) |
| Tissue Specificity | CDO1 antibody is human, mouse and rat reactive. |
Application
Western blot analysis of CDO1 in rat liver tissue lysate with CDO1 antibody at (A) 1 and (B) 2 μg/ml.| Positive Control | 1) Cat. No. 1464 - Rat Liver Tissue Lysate |
|---|---|
| Application Notes | CDO1 antibody can be used for detection of CDO1 by Western blot at 1 - 2 μg/ml. |
| Form | Liquid |
|---|---|
| Storage Instructions | CDO1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | CDO1 antibody is supplied in PBS containing 0.02% sodium azide. |
