Centromere-associated protein E, Centromere protein E, CENP-E, Kinesin-related protein CENPE, CENPE
Product description
Centrosome-associated protein E is a kinesin-like motor
protein that accumulates in the G2 phase of the cell cycle. Unlike
other centrosome-associated proteins, it is not present during
interphase and first appears at the centromere region of
chromosomes during prometaphase. CENPE is proposed to be one of the
motors responsible for mammalian chromosome movement and/or spindle
elongation.1) Kim, Y., et al. Cell 142(3):444-455(2010)
Immunogen
This CENPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2573-2601 amino acids from the C-terminal region of human CENPE.
Western blot analysis in Hela cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.