Application
Immunohistochemistry of CHADL in mouse skeletal muscle tissue with CHADL antibody at 5 μg/mL.Application
Western blot analysis of CHADL in mouse kidney tissue lysate with CHADL antibody at (A) 1 and (B) 2 μg/ml.| Product Name | CHADL Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Chondoadherin-like protein, SLRR4B |
| Product description | The Chondroadherin-like (CHADL) protein, also known as SLRR4B, is homologous to the Chondroadherin protein and is expressed cartillaginous tissues (1). Like Chondroadherin, CHADL belongs to the small leucine-rich proteoglycan (SLRP) family and class IV subfamily and plays a significant role in the regulation of chondrocyte growth and proliferation (1,2). CHADL is thought to play a negative regualtory role in collagen fibrillogenesis and chondrocyte differentiation (1).1) Tillgren V, Ho JC, Onnerfjord P, et al. The novel small leucine-rich protein chondroadherin-like (CHADL) is expressed in cartilage and modulates chondrocyte differentitation. J. Biol. Chem. 2015; 290:918-25. |
| Immunogen | CHADL antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human CHADL. The immunogen is located within the last 50 amino acids of CHADL. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| CHADL antibody can be used for the detection of CHADL by Western blot at 1 - 2 μg/mL. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CHADL |
|---|---|
| Alternative Names | Chondoadherin-like protein SLRR4B |
| Molecular Weight(MW) | Predicted: 84 kDa Observed: 86 kDa |
| Tissue Specificity | CHADL antibody is human, mouse and rat reactive. CHADL antibody is predicted to not cross-react with Chondroadherin protein. |
Application
Immunohistochemistry of CHADL in mouse skeletal muscle tissue with CHADL antibody at 5 μg/mL.
Application
Western blot analysis of CHADL in mouse kidney tissue lysate with CHADL antibody at (A) 1 and (B) 2 μg/ml.| Positive Control | 1) Cat. No. 1467 - Rat Skeletal Muscle Tissue Lysate |
|---|---|
| Application Notes | CHADL antibody can be used for the detection of CHADL by Western blot at 1 - 2 μg/mL. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | CHADL antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | CHADL Antibody is supplied in PBS containing 0.02% sodium azide. |
