Chromodomain-helicase-DNA-binding protein 1-like, Amplified in liver cancer protein 1, CHD1L, ALC1
Product description
In response to DNA strand breaks, chromatin adopts a
relaxed structure due to the addition of poly(ADP-ribose) (PAR) to
chromatin proteins by PARP enzymes (see PARP1; MIM 173870), and
this relaxation facilitates the repair of DNA damage. CHD1L
interacts with PAR and has a role in chromatin relaxation following
DNA damage (Ahel et al., 2009 [PubMed 19661379]).[supplied by
OMIM].1) Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Immunogen
This CHD1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 561-590 amino acids from the Central region of human CHD1L.
Western blot analysis in HepG2 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.