The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. Patients with dermatomyositis develop antibodies against the nuclear antigen chromodomain helicase DNA binding protein 4. The protein exists in a complex containing histone deacetylase and nucleosome remodeling activities, suggesting a role for chromatin reorganization in cancer metastasis.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAIHC
CHD4 antibody can be used in ELISA starting at 1:2000 - 1:10000, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 1:500, and immunoprecipitation:
Immunohistochemistry staining of CHD4 in cerebellum tissue using CHD4 Antibody.
Application Notes
CHD4 antibody can be used in ELISA starting at 1:2000 - 1:10000, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 1:500, and immunoprecipitation:
Additional Information
Form
Liquid
Storage Instructions
CHD4 antibody should be stored long term (months) at -20 ˚C and short term (weeks) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles.