This gene encodes a secreted protein that dorsalizes early
vertebrate embryonic tissues by binding to ventralizing
TGF-beta-like bone morphogenetic proteins and sequestering them in
latent complexes. The encoded protein may also have roles in
organogenesis and during adulthood. Multiple transcript variants
encoding distinct isoforms have been identified for this gene.
Other alternative splice variants have been described but their
full length sequence has not been determined.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This CHRD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 439-467 amino acids from the Central region of human CHRD.
Western blot analysis in mouse cerebellum tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.