The nicotinic acetylcholine receptors are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. Mutations in neuronal nicotinic acetylcholine receptor beta 2 subunit have been associated with autosomal dominant nocturnal frontal lobe epilepsies.1) Hales, T.G., et al., (2006) J. Biol. Chem. 281 (12), 8062-8071.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CHRNB2.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
CHRNB2 antibody can be used for detection of CHRNB2 by ELISA at 1:62500. CHRNB2 antibody can be used for detection of CHRNB2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
CHRNB2 antibody can be used for detection of CHRNB2 by ELISA at 1:62500. CHRNB2 antibody can be used for detection of CHRNB2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store CHRNB2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt