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CHRNG Antibody

Catalog Number:OM275476
OM275476
Discount Price
OM275476-100ul
1~2 Week
100ul
OM275476-50ul
50ul
OM275476-20ul
20ul
1~2 Week
Product Profile
Product Name CHRNG Antibody
Antibody Type Primary Antibodies
Antigen Alias CHRNG, ACHRG, MGC133376
Product description For background information on the acetylcholine receptor (AChR), see CHRNA1. Two forms of AChR are found in mammalian skeletal muscle cells. The mature form is predominant in innervated adult muscle and the embryonic form is present in fetal and denervated muscle. Embryonic and mature AChR differ by the replacement of the gamma subunit in the pentameric glycoprotein complex by its isoform, the epsilon subunit, which is specific to the mature AChR subtype. This switch is mediated by ARIA (acetylcholine receptor-inducing activity.For background information on the acetylcholine receptor (AChR), see CHRNA1 (MIM 100690). Two forms of AChR are found in mammalian skeletal muscle cells. The mature form is predominant in innervated adult muscle and the embryonic form is present in fetal and denervated muscle. Embryonic and mature AChR differ by the replacement of the gamma subunit in the pentameric glycoprotein complex by its isoform, the epsilon subunit (MIM 100725), which is specific to the mature AChR subtype. This switch is mediated by ARIA (acetylcholine receptor-inducing activity; MIM 142445).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2187 AK125362.1 1-21871) Morgan, N.V., (2006) Am. J. Hum. Genet. 79 (2), 390-395.
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CHRNG.
Key Feature
Clonality Polyclonal
Host Species Rabbit
Tested Applications ELISAWB
CHRNG antibody can be used for detection of CHRNG by ELISA at 1:312500. CHRNG antibody can be used for detection of CHRNG by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CHRNG
Alternative Names CHRNG
ACHRG
MGC133376
Molecular Weight(MW) 56 kDa
Database Links
Entrez Gene 1146
Protein Accession NP_005190
Application

Application

Antibody used in WB on Human MCF-7 at 1 ug/ml.
Positive Control 1) Cat. No. 1219 - MCF7 Cell Lysate
Application Notes CHRNG antibody can be used for detection of CHRNG by ELISA at 1:312500. CHRNG antibody can be used for detection of CHRNG by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store CHRNG antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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