Application
Western blot analysis in THP-1 cell line,human placenta,rat heart and skeletal muscle lysates (35ug/lane).| Product Name | CIR Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Corepressor interacting with RBPJ 1, CBF1-interacting corepressor, Recepin, CIR1, CIR |
| Product description | CIR may modulate splice site selection during alternative splicing of pre-mRNAs. It fegulates transcription and acts as corepressor for RBPSUH. It recruits RBPSUH to the Sin3-histone deacetylase complex (HDAC) and is required for RBPSUH-mediated repression of transcription.1) Olsen,J.V., Cell 127 (3), 635-648 (2006) |
| Immunogen | This CIR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-88 amino acids from the N-terminal region of human CIR. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CIR1 |
|---|---|
| Alternative Names | Corepressor interacting with RBPJ 1 CBF1-interacting corepressor Recepin CIR1 CIR |
| Molecular Weight(MW) | 52 kDa |
Application
Western blot analysis in THP-1 cell line,human placenta,rat heart and skeletal muscle lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
