| Product Name | CK2a (phospho Thr360 / Ser362) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CAP102, P53, CKII, CK2A1, CSNK2A1 |
| Product description | Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.1) Keller D. M., Zeng X., et al., Mol. Cell 7:283-292 (2001) Keller D. M., Lu H. et al., J. Biol. Chem. 277:50206-50213 (2002) Trembley J. H., Tatsumi S., et al., Mol. Cell. Biol. 25:1446-1457 (2005) Niefind K., Guerra B., et al., Acta Crystallogr. D 56:1680-1684 (2000) |
| Immunogen | CK2a (phospho-Thr360/Ser362) antibody was raised against a peptide sequence around phosphorylation site of threonine360/serine 362 (V-P-T (p) -P-S (p) -P-L) derived from Human CK2α. |
| Modification | p-Thr360 / Ser362 |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CTNNA1 |
|---|---|
| Alternative Names | CAP102 P53 CKII CK2A1 CSNK2A1 |
| Molecular Weight(MW) | 42 kDa |
| Tissue Specificity | This antibody detects endogenous level of CK2 only when phosphorylated at thronine 360. |
| Entrez Gene | 1495 |
|---|---|
| Protein Accession | NP_001894.2 |
| Application Notes | Western Blot: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
