Chloride channel protein ClC-Ka, Chloride channel Ka, ClC-K1, CLCNKA
Product description
This gene is a member of the CLC family of voltage-gated
chloride channels. The encoded protein is predicted to have 12
transmembrane domains, and requires a beta subunit called barttin
to form a functional channel. It is thought to function in salt
reabsorption in the kidney and potassium recycling in the inner
ear. The gene is highly similar to CLCNKB, which is located 10 kb
downstream from this gene. Multiple transcript variants encoding
different isoforms have been found for this gene. [provided by
RefSeq].1) Bailey, S.D., et al. Diabetes Care (2010) In press :
Immunogen
This CLCNKA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-47 amino acids from the N-terminal region of human CLCNKA.
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.