Application
Antibody used in IHC on Human Muscle.Application
Antibody used in WB on Transfected 293T at 0.2-1 ug/ml.| Product Name | CLDN11 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | CLDN11 belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.The protein encoded by this gene belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.1) Hosokawa, M., (2003) Glia 42 (4), 417-423. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLDN11. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISA,IHC,WB |
| CLDN11 antibody can be used for detection of CLDN11 by ELISA at 1:312500. CLDN11 antibody can be used for detection of CLDN11 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. | |
| Species Reactivity | Dog,Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CLDN11 |
|---|---|
| Alternative Names | CLDN11 OSP OTM |
| Molecular Weight(MW) | 22 kDa |
Application
Antibody used in IHC on Human Muscle.
Application
Antibody used in WB on Transfected 293T at 0.2-1 ug/ml.| Positive Control | 1) Tranfected 293T Cell Lysate |
|---|---|
| Application Notes | CLDN11 antibody can be used for detection of CLDN11 by ELISA at 1:312500. CLDN11 antibody can be used for detection of CLDN11 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store CLDN11 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
