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CNO6L Antibody

Catalog Number:OM275780
OM275780
Discount Price
OM275780-100ul
1~2 Week
100ul
OM275780-50ul
50ul
OM275780-20ul
20ul
1~2 Week
Product Profile
Product Name CNO6L Antibody
Antibody Type Primary Antibodies
Antigen Alias CNOT6L; CCR4B; CCR4-NOT transcription complex subunit 6-like; Carbon catabolite repressor protein 4 homolog B
Product description CNO6L plays a role in the deadenylation of mRNAs in the cytoplasm. CNO6L has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. CNO6L may be involved in the deadenylation-dependent degradation of mRNAs through the 3'-UTR AU-rich element-mediated mechanism. This protein involved in deadenylation-dependent degradation of CDKN1B mRNA.1) Miyasaka, T., et al. Cancer Sci. 99(4):755-761(2008)
Immunogen This CNO6L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-442 amino acids from the C-terminal region of human CNO6L.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications IHC-PWB
For IHC-P starting dilution is: 1:50~100 For WB starting dilution is: 1:1000:
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CNOT6L
Alternative Names CNOT6L
CCR4B
CCR4-NOT transcription complex subunit 6-like
Carbon catabolite repressor protein 4 homolog B
Molecular Weight(MW) 63 kDa
Sequence Similarities Predicted species reactivity based on immunogen sequence: Mouse
Database Links
Entrez Gene 246175
Protein Accession Q96LI5
Application

Application

CNO6L Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.

Application

Western blot analysis in Sk-Br-3 cell line tissue lysates (35ug/lane).
Application Notes For IHC-P starting dilution is: 1:50~100 For WB starting dilution is: 1:1000:
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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