Application
Immunohistochemistry of CNRIP1 in rat brain tissue with CNRIP1 antibody at 2.5 μg/ml.Application
Western blot analysis of CNRIP1 in human brain tissue lysate with CNRIP1 antibody at 1 μg/mL.Application
Immunofluorescence of CNRIP1 in rat brain tissue with CNRIP1 antibody at 20 μg/ml.| Product Name | CNRIP1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CNRIP1 Antibody: CRIP1, C2orf32, CB1 cannabinoid receptor-interacting protein 1, CRIP-1 |
| Product description | CNRIP1 Antibody: The CNRIP1 (cannabinoid receptor interacting protein 1) protein is a G-protein coupled receptor which interacts with the C-terminal tail of cannabinoid receptor 1 (CB1) and is thought to play a role in synaptic plasticity, analgesia, appetite, and neuroprotection. One isoform of CNRIP1, CNRIP1a, modulates the constitutive CB1 receptor activity in the central nervous system (CNS), while the role of the shorter isoform CNRIP1b is yet unknown. CNRIP1 has been suggested as a potential target for CNS drug discovery.1) Niehaus JL, Liu Y, Wallis KT, et al. CB1 cannabinoid receptor activity is modulated by the cannabinoid receptor interacting protein CRIP 1a. Mol. Pharmacol. 2007; 72:1557-66. |
| Immunogen | CNRIP1 antibody was raised against a 15 amino acid peptide near the center of human CNRIP1. The immunogen is located within amino acids 50 - 100 of CNRIP1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| CNRIP1 antibody can be used for detection of CNRIP1 by Western blot at 1 - 2 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CNRIP1 |
|---|---|
| Alternative Names | CNRIP1 Antibody: CRIP1 C2orf32 CB1 cannabinoid receptor-interacting protein 1 CRIP-1 |
| Molecular Weight(MW) | Predicted: 18 kDa Observed: 16 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Bovine: (93%) |
| Tissue Specificity | At least two isoforms of CNRIP1 are known to exist; this antibody will detect both isoforms. |
Application
Immunohistochemistry of CNRIP1 in rat brain tissue with CNRIP1 antibody at 2.5 μg/ml.
Application
Western blot analysis of CNRIP1 in human brain tissue lysate with CNRIP1 antibody at 1 μg/mL.
Application
Immunofluorescence of CNRIP1 in rat brain tissue with CNRIP1 antibody at 20 μg/ml.| Positive Control | 1) Cat. No. 1303 - Human Brain Tissue Lysate |
|---|---|
| Application Notes | CNRIP1 antibody can be used for detection of CNRIP1 by Western blot at 1 - 2 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | CNRIP1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | CNRIP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
