This gene encodes the alpha chain of type X collagen, a
short chain collagen expressed by hypertrophic chondrocytes during
endochondral ossification. Unlike type VIII collagen, the other
short chain collagen, type X collagen is a homotrimer. Mutations in
this gene are associated with Schmid type metaphyseal
chondrodysplasia (SMCD) and Japanese type spondylometaphyseal
dysplasia (SMD).1) Makitie, O., et al. J. Orthop. Res. 28(11):1497-1501(2010)
Immunogen
This COL10A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human COL10A1.
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.