This gene encodes the pro-alpha1 chains of type III
collagen, a fibrillar collagen that is found in extensible
connective tissues such as skin, lung, uterus, intestine and the
vascular system, frequently in association with type I collagen.
Mutations in this gene are associated with Ehlers-Danlos syndrome
types IV, and with aortic and arterial aneurysms. Two transcripts,
resulting from the use of alternate polyadenylation signals, have
been identified for this gene. [provided by R. Dalgleish].1) Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Immunogen
This COL3A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1410-1438 amino acids from the C-terminal region of human COL3A1.
Western blot analysis in T47D cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.