Application
Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.Application
Antibody used in IHC on Human Heart.| Product Name | COPS5 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | COPS5, CSN5, JAB1, SGN5, MOV-34 |
| Product description | The protein encoded by COPS5 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors.1) Oono, K., et al., (2004) Neurochem. Int. 45 (5), 765-772. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COPS5. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| COPS5 antibody can be used for detection of COPS5 by ELISA at 1:62500. COPS5 antibody can be used for detection of COPS5 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | COPS5 |
|---|---|
| Alternative Names | COPS5 CSN5 JAB1 SGN5 MOV-34 |
| Molecular Weight(MW) | 38 kDa |
Application
Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.
Application
Antibody used in IHC on Human Heart.| Positive Control | 1) Cat. No. 1211 - HepG2 Cell Lysate |
|---|---|
| Application Notes | COPS5 antibody can be used for detection of COPS5 by ELISA at 1:62500. COPS5 antibody can be used for detection of COPS5 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store COPS5 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
