JAB-1 is a 38 kDa protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the """"Signalosome"""", which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants, which is important in light-mediated plant development. Although the specific function of JAB-1 in this complex is unclear, it has recently been implicated in targeting proteins for degradation by the proteasome.
Immunogen
COPS5 monoclonal antibody was raised against a peptide located in the full - length mouse E. coli expressedCOPS5 (Mouse).
Key Feature
Clonality
Monoclonal
Isotype
IgG2b
Host Species
Mouse
Tested Applications
IFIHCIPWB
COPS5 antibody can be used in Western Blot starting at 1 - 2 μg/mL, and immunohistochemistry starting at 10 μg/mL.: