Application
Western blot analysis of CPEB1 in rat brain tissue lysate with CPEB1 antibody at (A) 1 and (B) 2 μg/mL.| Product Name | CPEB1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CPEB1 Antibody: CEBP, CPEB, CPEB-1, CPE-BP1, hCPEB-1, Cytoplasmic polyadenylation element-binding protein 1 |
| Product description | CPEB1 Antibody: CPEB1 is an RNA binding protein that contains an RNA-recognition motif and a zinc finger-containing region found in a wide range of vertebrates and invertebrates. CPEB1 forms the nucleus of a complex of factors that regulate poly(A) elongation and promotes polyadenylation-induced translation. CPEB1 mediates many diverse biological processes such as germ cell development, cell division and senescence, and synaptic plasticity. Recently, it was discovered that CPEB1 is involved in beta-catenin mRNA translation and cell migration in astrocytes as well as regulating hypoxia-inducible factor (HIF)-1 expression, demonstrating the wide range of processes in which CPEB1 plays a role. At least four isoforms of CPEB1 are known to exist.1) Richter JD. CPEB: a life in translation. Trends in Biochem. Sci.2007; 32:179-85. |
| Immunogen | CPEB1 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human CPEB1. The immunogen is located within amino acids 50 - 100 of CPEB1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| CPEB1 antibody can be used for detection of CPEB1 by Western blot at 1 - 2 μg/mL.: |
|
| Species Reactivity | MouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CPEB1 |
|---|---|
| Alternative Names | CPEB1 Antibody: CEBP CPEB CPEB-1 CPE-BP1 hCPEB-1 Cytoplasmic polyadenylation element-binding protein 1 |
Application
Western blot analysis of CPEB1 in rat brain tissue lysate with CPEB1 antibody at (A) 1 and (B) 2 μg/mL.| Positive Control | 1) Cat. No. 1463 - Rat Brain Tissue Lysate |
|---|---|
| Application Notes | CPEB1 antibody can be used for detection of CPEB1 by Western blot at 1 - 2 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | CPEB1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | CPEB1 Antibody is supplied in PBS containing 0.02% sodium azide. |
