Application
Antibody used in IHC on Human Heart.Application
Antibody used in WB on Transfected 293T at 0.2-1 ug/ml.| Product Name | CPN1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CPN1, CPN, FLJ40792, SCPN |
| Product description | Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency.Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.1) Skidgel, R.A. (2007) Int. Immunopharmacol. 7 (14), 1888-1899. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CPN1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| CPN1 antibody can be used for detection of CPN1 by ELISA at 1:1562500. CPN1 antibody can be used for detection of CPN1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CPN1 |
|---|---|
| Alternative Names | CPN1 CPN FLJ40792 SCPN |
| Molecular Weight(MW) | 50 kDa |
Application
Antibody used in IHC on Human Heart.
Application
Antibody used in WB on Transfected 293T at 0.2-1 ug/ml.| Positive Control | 1) Tranfected 293T Cell Lysate |
|---|---|
| Application Notes | CPN1 antibody can be used for detection of CPN1 by ELISA at 1:1562500. CPN1 antibody can be used for detection of CPN1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store CPN1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
