The adenovirus E1A protein both activates and represses
gene expression to promote cellular proliferation and inhibit
differentiation. The protein encoded by this gene antagonizes
transcriptional activation and cellular transformation by E1A. This
protein shares limited sequence similarity with E1A and binds both
the general transcription factor TBP and the tumor suppressor pRb
in vitro. This gene may contribute to the transcriptional control
of cell growth and differentiation.1) Han, Y., et al. J. Mol. Cell. Cardiol. 48(6):1225-1235(2010)
Immunogen
This CREG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-45 amino acids from the N-terminal region of human CREG1.
Western blot analysis in mouse heart tissue lysates (35ug/lane).
Application
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.