Application
Antibody used in IHC on Human Stomach at 4.0-8.0 ug/ml.Application
Antibody used in WB on Human Placenta at 1.25 ug/ml.| Product Name | CSH1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | CSH1 is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome.The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome.1) Walsh, S.T. (2006) J. Mol. Biol. 358 (3), 773-784. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CSH1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| CSH1 antibody can be used for detection of CSH1 by ELISA at 1:312500. CSH1 antibody can be used for detection of CSH1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CSH1 |
|---|---|
| Alternative Names | CSH1 PL CSA CS-1 CSMT hCS-1 hCS-A |
| Molecular Weight(MW) | 24 kDa, 15 kDa, 25 kDa, 25 kDa, 16 kDa, 23 kDa, 29 kDa, 19 kDa |
Application
Antibody used in IHC on Human Stomach at 4.0-8.0 ug/ml.
Application
Antibody used in WB on Human Placenta at 1.25 ug/ml.| Positive Control | 1) Cat. No. 1309 - Human Placenta Lysate |
|---|---|
| Application Notes | CSH1 antibody can be used for detection of CSH1 by ELISA at 1:312500. CSH1 antibody can be used for detection of CSH1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store CSH1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
