Application
Immunofluorescence of CTRP3 in Mouse Heart tissue with CTRP3 antibody at 10 μg/mL.| Product Name | CTRP3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | CTRP3 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. It has been suggested that CTRP3 may play a role in skeletal development.1) Fantuzzi G. Adipose tissue, adipokines, and inflammation. J. Allergy Clin. Immunol. 2005; 115:911-9. |
| Immunogen | CTRP3 antibody was raised against a 16 amino acid synthetic peptide from near the center of human CTRP3. The immunogen is located within the first 50 amino acids of CTRP3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IFIHC-P |
| CTRP3 antibody can be used for the detection of CTRP3 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2 μg/mL. For immunofluorescence start at 10 μg/mL. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | C1QTNF3 |
|---|---|
| Alternative Names | CTRP3 Antibody: CORS CORCS CTRP3 CORS26 C1ATNF3 CORS-26 UNQ753/PRO1484 Complement C1q tumor necrosis factor-related protein 3 Collagenous repeat-containing sequence 26 kDa protein |
| Molecular Weight(MW) | Predicted: 35 kDa Observed: 36 kDa |
| Tissue Specificity | Multiple isoforms of CTRP3 are known to exist. CTRP3 antibody is predicted to not recognize other members of the CTRP protein family. |
Application
Immunofluorescence of CTRP3 in Mouse Heart tissue with CTRP3 antibody at 10 μg/mL.| Positive Control | 1) Cat. No. 1401 - Mouse Heart Tissue Lysate |
|---|---|
| Application Notes | CTRP3 antibody can be used for the detection of CTRP3 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2 μg/mL. For immunofluorescence start at 10 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | CTRP3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | CTRP3 Antibody is supplied in PBS containing 0.02% sodium azide. |
