Application
Western blot analysis of CTRP5 in caco-2 cell lysate with CTRP5 antibody at (A) 1, (B) 2, and (C) 4 μg/mL.| Product Name | CTRP5 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | CTRP5 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. CTRP5 has been suggested to be involved in age-related macular degeneration.1) CTRP5 antibody can be stored at 4˚C, stable for one year. Fantuzzi G. Adipose tissue, adipokines, and inflammation. J. Allergy Clin. Immunol. 2005; 115:911-9. |
| Immunogen | CTRP5 antibody was raised against a 15 amino acid synthetic peptide from near the center of human CTRP5. The immunogen is located within amino acids 90 - 140 of CTRP5. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| CTRP5 antibody can be used for the detection of CTRP5 by Western blot at 1 - 4 μg/mL. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | C1QTNF5 |
|---|---|
| Alternative Names | CTRP5 Antibody: CTRP5 CTRP5 UNQ303/PRO344 Complement C1q tumor necrosis factor-related protein 5 |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Rat: (93%) |
| Tissue Specificity | Adipokine proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size. |
Application
Western blot analysis of CTRP5 in caco-2 cell lysate with CTRP5 antibody at (A) 1, (B) 2, and (C) 4 μg/mL.| Positive Control | 1) Cat. No. 1223 - Caco-2 Cell Lysate |
|---|---|
| Application Notes | CTRP5 antibody can be used for the detection of CTRP5 by Western blot at 1 - 4 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | CTRP5 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | CTRP5 Antibody is supplied in PBS containing 0.02% sodium azide. |
