| Product Name | CTRP5 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | CTRP5 (C1qTNF-related protein 5; C1QTNF5) belongs to a highly conserved family of adiponectin paralogs. CTRP5 mediates activation of AMP-activated protein kinase (AMPK) in muscle and liver cells, thereby regulating glucose and lipid metabolism. Serum levels of CTRP5 are significantly higher in obese/diabetic animal models compared to normal controls. Furthermore, CTRP5 may be a putative biomarker for mitochondrial dysfunction. Defects in C1QTNF5 are a cause of late-onset retinal degeneration (LORD). |
| Immunogen | Recombinant human CTRP5. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| ELISA: (direct and indirect: 1:2,000-1:5,000). Western Blot: (1:2,000-1:5,000 using ECL suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | C1QTNF5 |
|---|---|
| Alternative Names | Complement C1q Tumor Necrosis Factor-related Protein 5 C1QTNF5 |
| Tissue Specificity | Recognizes the N-terminal half of CTRP5 full-length protein. Detects bands of ~15kDa and ~26kDa by Western blot. |
| Application Notes | ELISA: (direct and indirect: 1:2,000-1:5,000). Western Blot: (1:2,000-1:5,000 using ECL suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Stable for at least 6 months after receipt when stored at -20˚C. |
| Storage Buffer | Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives. |
