CTRP7 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Like the other members of the adiponectin and CTRP protein family, the mature CTRP7 is secreted and can be found in the organism's circulatory system.1) Fantuzzi G. Adipose tissue, adipokines, and inflammation. J. Allergy Clin. Immunol. 2005; 115:911-9.
Immunogen
CTRP7 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human CTRP7. The immunogen is located within the first 50 amino acids of CTRP7.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAICCWB
CTRP7 antibody can be used for the detection of CTRP7 by Western blot at 1 - 4 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL.
Immunohistochemical staining of rat brain tissue using CTRP7 antibody at 10 μg/mL.
Application
Western blot analysis of CTRP7 in 3T3 cell lysate with CTRP7 antibody at (A) 1, (B) 2, and (C) 4 μg/mL.
Positive Control
1) Cat. No. 1212 - 3T3 Cell Lysate
Application Notes
CTRP7 antibody can be used for the detection of CTRP7 by Western blot at 1 - 4 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL.
Additional Information
Form
Liquid
Storage Instructions
CTRP7 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer
CTRP7 Antibody is supplied in PBS containing 0.02% sodium azide.