Application
Immunohistochemistry staining of Cullin 7 in brain cortex tissue using Cullin 7 Antibody.| Product Name | Cullin 7 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. Cullin 7 is a component of E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Cullin 7 seems to be involved proteosomal degradation of proteins involved in endothelial proliferation and/or differentiation. Cullin 7 is part of a SCF-like complex consisting of CUL7, RBX1, SKP1, FBXW8 and GLMN isoform 1. Cullin 7 interacts with a complex of SKP1 and FBXW8, but not with SKP1 alone. |
| Immunogen | Cullin 7 antibody was raised against a peptide near the C-Terminus of Cullin 7 (Human) Amino acids 1679-1698. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCIPWB |
| Cullin 7 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 5 μg/mL. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CUL7 |
|---|---|
| Alternative Names | CUL7 Cullin 7 Cullin-7 CUL-7 DJ20C7.5 KIAA0076 |
Application
Immunohistochemistry staining of Cullin 7 in brain cortex tissue using Cullin 7 Antibody.| Application Notes | Cullin 7 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 5 μg/mL. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store Cullin 7 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | Serum, 0.01% sodium azide. |
