Application
Western blot analysis of extracts from K562 tissue using Cyclin D1 (Phospho-Ser90) Antibody. The lane on the right is treated with the antigen-specific peptide.| Product Name | Cyclin D1 (phospho Ser90) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1. Ubiquitinates STUB1-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.1) Sewing A, Müller R (1994) Oncogene 9, 2733-6 |
| Immunogen | Cyclin D1 (phospho Ser90) antibody was raised against a peptide sequence around phosphorylation site of serine 90 (F-L-S (p)-L-E) derived from Human Cyclin D1 . |
| Modification | p-Ser90 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CCND1 |
|---|---|
| Alternative Names | BCL1 CCND1 CYL-1 PRAD1 PRAD1 oncogene |
| Molecular Weight(MW) | 31 kDa |
| Tissue Specificity | The antibody detects endogenous level of Cyclin D1 only when phosphorylated at serine 90. |
| Entrez Gene | 595 |
|---|---|
| Protein Accession | NP_444284.1 |
Application
Western blot analysis of extracts from K562 tissue using Cyclin D1 (Phospho-Ser90) Antibody. The lane on the right is treated with the antigen-specific peptide.| Application Notes | Western Blot: 1:500~1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
