Application
Antibody used in WB on Human Liver at 2.5 ug/ml.| Product Name | CYP3A7 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CYP3A7, CP37, P450-HFLA, CYPIIIA7 |
| Product description | CYP3A7 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1.This gene, CYP3A7, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced.1) Sim, S.C., (2005) Pharmacogenet. Genomics 15 (9), 625-631. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CYP3A7. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| CYP3A7 antibody can be used for detection of CYP3A7 by ELISA at 1:312500. CYP3A7 antibody can be used for detection of CYP3A7 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CYP3A7 |
|---|---|
| Alternative Names | CYP3A7 CP37 P450-HFLA CYPIIIA7 |
| Molecular Weight(MW) | 57 kDa |
Application
Antibody used in WB on Human Liver at 2.5 ug/ml.| Positive Control | 1) Cat. No. XBL-10409 - Fetal Liver Tissue Lysate |
|---|---|
| Application Notes | CYP3A7 antibody can be used for detection of CYP3A7 by ELISA at 1:312500. CYP3A7 antibody can be used for detection of CYP3A7 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store CYP3A7 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
