Application
Western blot analysis in HL-60 cell line lysates (35ug/lane).| Product Name | DBNL Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Drebrin-like protein, Cervical SH3P7, Cervical mucin-associated protein, Drebrin-F, HPK1-interacting protein of 55 kDa, HIP-55, SH3 domain-containing protein 7, DBNL, CMAP, SH3P7 |
| Product description | Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic function. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin.1) Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009) |
| Immunogen | This DBNL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-319 amino acids from the C-terminal region of human DBNL. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DBNL |
|---|---|
| Alternative Names | Drebrin-like protein Cervical SH3P7 Cervical mucin-associated protein Drebrin-F HPK1-interacting protein of 55 kDa HIP-55 SH3 domain-containing protein 7 DBNL CMAP SH3P7 |
| Molecular Weight(MW) | 48 kDa |
Application
Western blot analysis in HL-60 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
