This gene encodes a member of the WD repeat protein
family. WD repeats are minimally conserved regions of approximately
40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD),
which may facilitate formation of heterotrimeric or multi-protein
complexes. Members of this family are involved in a variety of
cellular processes, including cell cycle progression, signal
transduction, apoptosis, and gene regulation. This gene appears to
represent an intronless retrocopy of a related multi-exon gene
located on chromosome 9. However, the CDS of this intronless gene
remains intact, it is conserved in other mammalian species, it is
known to be transcribed, and it is therefore thought to encode a
functional protein.1) Jin, J., et al. Mol. Cell 23(5):709-721(2006)
Immunogen
This DCAF12L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-338 amino acids from the C-terminal region of human DCAF12L2.
Western blot analysis in A2058 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.