Application
Antibody used in WB on Human Jurkat 0.2-1 ug/ml.| Product Name | DCP2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DCP2, FLJ33245, NUDT20 |
| Product description | DCP2 is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. DCP2 removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. It has higher activity towards mRNAs that lack a poly (A) tail, but has no activity towards a cap structure lacking a RNA moiety.DCP2 is a key component of an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).1) Yamochi, T., (2008) Biochem. Biophys. Res. Commun. 370 (1), 195-199. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DCP2. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| DCP2 antibody can be used for detection of DCP2 by ELISA at 1:62500. DCP2 antibody can be used for detection of DCP2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DCP2 |
|---|---|
| Alternative Names | DCP2 FLJ33245 NUDT20 |
| Molecular Weight(MW) | 48 kDa |
Application
Antibody used in WB on Human Jurkat 0.2-1 ug/ml.| Positive Control | 1) Cat. No. 1205 - Jurkat Cell Lysate |
|---|---|
| Application Notes | DCP2 antibody can be used for detection of DCP2 by ELISA at 1:62500. DCP2 antibody can be used for detection of DCP2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store DCP2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
