Application
Western blot analysis of Dcr-1 antibody in CEM cell line lysates (35ug/lane)| Product Name | Dcr-1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Endoribonuclease dcr-1, 3126-, dcr-1 |
| Product description | The Dcr-1 gene encodes a bidentate ribonuclease that is homologous to E. coli RNAse III. Dcr-1 is required both for RNA interference and for synthesis of small developmental RNAs. Dcr-1 interacts in vivo with RDE-4, a double-stranded RNA (dsRNA) binding protein required for RNAi that interacts with trigger dsRNAs and may function to deliver dsRNAs to Dcr-1 for endonucleolytic processing.1) Duchaine TF, et al. 2006. Cell 124:343-354. |
| Immunogen | This Dcr-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1068-1097 amino acids from the Central region of human Dcr-1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | C.elegans |
| Concentration | 1mg/ml |
| Gene Symbol | dcr-1 |
|---|---|
| Alternative Names | Endoribonuclease dcr-1 3126- dcr-1 |
| Molecular Weight(MW) | 218 kDa |
Application
Western blot analysis of Dcr-1 antibody in CEM cell line lysates (35ug/lane)| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
