Probable ATP-dependent RNA helicase DDX28, Mitochondrial DEAD box protein 28, DDX28, MDDX28
Product description
DEAD box proteins, characterized by the conserved motif
Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are
implicated in a number of cellular processes involving alteration
of RNA secondary structure, such as translation initiation, nuclear
and mitochondrial splicing, and ribosome and spliceosome assembly.
Based on their distribution patterns, some members of the DEAD box
protein family are believed to be involved in embryogenesis,
spermatogenesis, and cellular growth and division. This gene is
intronless. It encodes an RNA-dependent ATPase. The encoded protein
is localized in the mitochondria and the nucleus, and can be
transported between the mitochondria and the nucleus. [provided by
RefSeq].1) Bogenhagen, D.F., et al. J. Biol. Chem. 283(6):3665-3675(2008)
Immunogen
This DDX28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 370-398 amino acids from the C-terminal region of human DDX28.
Western blot analysis in A549 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.