DEF6, or IBP, is a guanine nucleotide exchange factor
(GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly
expressed in B and T cells (Gupta et al., 2003 [PubMed
12923183]).1) Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
Immunogen
This DEF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 500-528 amino acids from the C-terminal region of human DEF6.
Western blot analysis in A375 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.