DEK was first identified in a fusion with the CAN nucleoporin protein in a specific subtype of acute myelogenous leukemia. DEK has also been shown to be an autoantigen in patients with pauciarticular onset juvenile rheumatoid arthritis. Further, the last 65 amino acids of DEK can partially reverse the mutation-prone phenotype of cells from patients with ataxia-telangiectasia1) Orlic, M., et al., (2006) Genes Chromosomes Cancer 45 (1), 72-82.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DEK.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
DEK antibody can be used for detection of DEK by ELISA at 1:62500. DEK antibody can be used for detection of DEK by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
DEK antibody can be used for detection of DEK by ELISA at 1:62500. DEK antibody can be used for detection of DEK by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store DEK antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt