Application
Antibody used in WB on Human Jurkat 5.0 ug/ml.| Product Name | DES Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DES, CMD1I, CSM1, CSM2, FLJ12025, FLJ39719, FLJ41013, FLJ41793, LGMD2R |
| Product description | DES is a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in its gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.1) Fidzianska, A., (2005) Neuromuscul. Disord. 15 (8), 525-531. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DES. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| DES antibody can be used for detection of DES by ELISA at 1:312500. DES antibody can be used for detection of DES by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | DES |
|---|---|
| Alternative Names | DES CMD1I CSM1 CSM2 FLJ12025 FLJ39719 FLJ41013 FLJ41793 LGMD2R |
| Molecular Weight(MW) | 52 kDa |
Application
Antibody used in WB on Human Jurkat 5.0 ug/ml.| Positive Control | 1) Cat. No. 1205 - Jurkat Cell Lysate |
|---|---|
| Application Notes | DES antibody can be used for detection of DES by ELISA at 1:312500. DES antibody can be used for detection of DES by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store DES antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
