Protein DGCR14, DiGeorge syndrome critical region 13, DiGeorge syndrome critical region 14, DiGeorge syndrome protein H, DGS-H, Protein ES2, DGCR14, DGCR13, DGSH, DGSI, ES2
Product description
This gene is located within the minimal DGS critical
region (MDGCR) thought to contain the gene(s) responsible for a
group of developmental disorders. These disorders include DiGeorge
syndrome, velocardiofacial syndrome, conotruncal anomaly face
syndrome, and some familial or sporadic conotruncal cardiac defects
which have been associated with microdeletion of 22q11.2. The
encoded protein may be a component of C complex spliceosomes, and
the orthologous protein in the mouse localizes to the nucleus.1) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Immunogen
This DGCR14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-244 amino acids from the Central region of human DGCR14.
Protein DGCR14 DiGeorge syndrome critical region 13 DiGeorge syndrome critical region 14 DiGeorge syndrome protein H DGS-H Protein ES2 DGCR14 DGCR13 DGSH DGSI ES2
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.