Application
Western blot analysis of Dok5 using rabbit polyclonal Dok5 Antibody (PTB domain) using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Dok5 gene.| Product Name | Dok5 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Docking protein 5, Downstream of tyrosine kinase 5, Insulin receptor substrate 6, IRS-6, IRS6, DOK5, C20orf180 |
| Product description | DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.1) Liu, X., et al.Am Acad Child Adolesc Psychiatry 49(1):33-41(2010) |
| Immunogen | This Dok5 antibody is generated from rabbits immunized with a recombinant protein (GST-tag removed) from human Dok5. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | DOK5 |
|---|---|
| Alternative Names | Docking protein 5 Downstream of tyrosine kinase 5 Insulin receptor substrate 6 IRS-6 IRS6 DOK5 C20orf180 |
| Molecular Weight(MW) | 35 kDa |
Application
Western blot analysis of Dok5 using rabbit polyclonal Dok5 Antibody (PTB domain) using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Dok5 gene.| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
