Application
Western blot of 5 μg of bovine adrenal medulla lysate showing specific immunolabeling of the ~55k DOPA decarboxylase protein.| Product Name | DOPA Decarboxylase Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AADC, AADC, DOPA decarboxylase, |
| Product description | DOPA decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).1) Berry MD, Juorio AV, Li XM, Boulton AA (1996) Aromatic L-amino acid decarboxylase: a neglected and misunderstood enzyme. Neurochem Res 21:1075-1087. |
| Immunogen | Peptide from N-terminus region of human DOPA decarboxylase (DDC), conjugated to keyhole limpet hemocyanin (KLH). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| The antibody has been directly tested for reactivity in Western blots in bovine, canine, guinea pig, human, rabbit, rat and sheep tissues.: |
|
| Species Reactivity | BovineDogGoatHumanRabbitRatSheep |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DDC |
|---|---|
| Alternative Names | AADC AADC DOPA decarboxylase |
| Molecular Weight(MW) | 55 |
Application
Western blot of 5 μg of bovine adrenal medulla lysate showing specific immunolabeling of the ~55k DOPA decarboxylase protein.| Application Notes | The antibody has been directly tested for reactivity in Western blots in bovine, canine, guinea pig, human, rabbit, rat and sheep tissues.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | DOPA Decarboxylase antibody can be stored at -20˚C and is stable at -20˚C for at least 1 year. |
| Storage Buffer | 100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol. |
Data sheet for OM277288