Application
Immunofluorescence of DDC in human lung tissue with DDC antibody at 20 μg/mL.Application
Immunohistochemistry of DDC in human lung tissue with DDC antibody at 2.5 μg/mL.Application
Western blot analysis of DDC in human lung tissue lysate with DDC antibody at (A) 0.5 and (B) 1 μg/ml.Application
Immunohistochemistry of DDC in human lung tissue with DDC antibody at 2.5 μg/mL.Application
Immunofluorescence of DDC in human lung tissue with DDC antibody at 20 μg/mL.Application
Western blot analysis of DDC in human lung tissue lysate with DDC antibody at (A) 0.5 and (B) 1 μg/ml.| Product Name | DDC Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | DOPA decarboxylase (DDC) belongs to the group II decarboxylase family of proteins (1). It is an important protein in the catecholamine biosynthesis pathway. DDC catalyzes the second reaction in the biosynthesis of catecholamines, trace amines and serotonin (1,2). It can form a homodimer and is expressed in the central nervous system (2). DDC can be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease, neuroendocrine tumors and drug abuse (3,4). Defects in DDC gene may cause the autosomal recessive disorder AADC deficiency (4).1) Berry MD, Juorio AV, Li XM, et al. Aromatic L-amino acid decarboxylase: a neglected and misunderstood enzyme. Neurochem. Res. 1996; 21:1075-87. |
| Immunogen | DDC antibody was raised against a 14 amino acid peptide near the carboxy terminus of human DDC. The immunogen is located within amino acids 390 - 440 of DDC . |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| DDC antibody can be used for detection of DDC by Western blot at 1 - 2 μg/ml. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DDC |
|---|---|
| Alternative Names | DDC Antibody : AADC AADC Aromatic-L-amino-acid decarboxylase DOPA decarboxylase |
| Molecular Weight(MW) | Predicted: 53 kDa Observed: 53 kDa |
| Sequence Similarities | 2) Cat. No. 10-101 - Human Lung Tissue Slide |
| Tissue Specificity | DDC antibody is human, mouse and rat reactive. |
Application
Immunofluorescence of DDC in human lung tissue with DDC antibody at 20 μg/mL.
Application
Immunohistochemistry of DDC in human lung tissue with DDC antibody at 2.5 μg/mL.
Application
Western blot analysis of DDC in human lung tissue lysate with DDC antibody at (A) 0.5 and (B) 1 μg/ml.
Application
Immunohistochemistry of DDC in human lung tissue with DDC antibody at 2.5 μg/mL.
Application
Immunofluorescence of DDC in human lung tissue with DDC antibody at 20 μg/mL.
Application
Western blot analysis of DDC in human lung tissue lysate with DDC antibody at (A) 0.5 and (B) 1 μg/ml.| Positive Control | 1) Cat. No. 1302 - Human Lung Tissue Lysate |
|---|---|
| Application Notes | DDC antibody can be used for detection of DDC by Western blot at 1 - 2 μg/ml. |
| Form | Liquid |
|---|---|
| Storage Instructions | DDC antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | DDC Antibody is supplied in PBS containing 0.02% sodium azide. |
Data sheet for OM276838