Application
Immunohistochemistry staining of DRD1 in brain tissue using DRD1 Antibody.| Product Name | DRD1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DRD1, D(1A) dopamine receptor, D1a dopamine receptor, Dopamine d-1 receptor, Dopamine receptor d1a, DRD1A, DADR, Dopamine d1a receptor, Dopamine receptor D1, Dopamine 1 receptor, Dopamine type 1 receptor, D-1 dopamine receptor, D1 dopamine receptor, D1a re |
| Product description | DRD1, a Dopamine Receptor, mediates the effect of the neurotransmitter dopamine, an intermediate in the biosynthesis of noradrenaline and adrenaline. It is involved in the control of motor activity and cognitive memory. Downregulation of DRD1 leads to severe impairments in working memory and to locomotor hyperactivity, which are observed in diseases such as schizophrenia, Parkinson's disease, affective disorders, and attention deficit hyperactivity disorder. DRD1 enhances smooth muscle contraction and vasodilation in the heart. It also modulates sodium transport in the kidney and is involved in the pathogenesis of hypertension. |
| Immunogen | DRD1 antibody was raised against a peptide located in the C-Terminal cytoplasmic domain of DRD1 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHC |
| DRD1 antibody can be used in immunohistochemistry starting at 10 μg/mL.: |
|
| Species Reactivity | GibbonGorillaHumanMonkeyRabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DRD1 |
|---|---|
| Alternative Names | DRD1 D(1A) dopamine receptor D1a dopamine receptor Dopamine d-1 receptor Dopamine receptor d1a DRD1A DADR Dopamine d1a receptor Dopamine receptor D1 Dopamine 1 receptor Dopamine type 1 receptor D-1 dopamine receptor D1 dopamine receptor D1a re |
| Tissue Specificity | BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Application
Immunohistochemistry staining of DRD1 in brain tissue using DRD1 Antibody.| Application Notes | DRD1 antibody can be used in immunohistochemistry starting at 10 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | DRD1 antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
