Application
Antibody is used in Western blot to detect Drosophila Parkin in, from left to right, mouse kidney, mouse brain, mouse heart, Ramos, and Hela tissue lysates.| Product Name | Drosophila Parkin Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CG10523-PB; isoform B; Cg10523-pc; isoform c; PARKIN; park; parkin; |
| Product description | Parkin is thought to play a role in the ubiquitin/proteasome pathway for protein degradation. The amino terminus bears sequence homology to ubiquitin while functionally it acts as a RING-type ubiquitin protein ligase (E3) that coordinates the transfer of ubiquitin to substrate proteins, thus targeting them for degradation by the proteasome. Mutations in the human version of the protein are known to cause autosomal recessive juvenile parkinsonism.1) Zhong,L. et al. J. Biol. Chem. 280 (10), 9425-9430 (2005) |
| Immunogen | This Drosophila Parkin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-111 amino acids from the N-terminal region of human Drosophila Parkin. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Drosophila |
| Concentration | 1mg/ml |
| Gene Symbol | Q7KTX7 |
|---|---|
| Alternative Names | CG10523-PB isoform B Cg10523-pc isoform c PARKIN park parkin |
| Molecular Weight(MW) | 54 kDa |
Application
Antibody is used in Western blot to detect Drosophila Parkin in, from left to right, mouse kidney, mouse brain, mouse heart, Ramos, and Hela tissue lysates.| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
